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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 12240Generated: October 26, 2026

Piperidine → (S)-6,6-Dimethyl-4-(2-oxo-2-piperidin-1-yl-ethyl)morpholine-3-carboxylic acid (6-chloro-9H-beta-carbolin-8-yl)-amide

https://huagongshe.com/reaction/12240

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
Reactant[(S)-5-(6-Chloro-9H-beta-carbolin-8-ylcarbamoyl)-2,2-dimethyl-morpholin-4-yl]-acetic acidHCID 11384512—
Product(S)-6,6-Dimethyl-4-(2-oxo-2-piperidin-1-yl-ethyl)morpholine-3-carboxylic acid (6-chloro-9H-beta-carbolin-8-yl)-amideHCID 1160546390%

Reaction Steps

The desired compound was prepared according to Method F from [(S)-5-(6-Chloro-9H-beta-carbolin-8-ylcarbamoyl)-2,2-dimethyl-morpholin-4-yl]-acetic acid and piperidine in 90% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07727985B2
Source datasetuspto-grants-2010_06
ORD IDord-86725e0e521e4e15b28a05337dd003f8
Source noteuspto-grants-2010_06