Methyl 5-bromopyridine-3-carboxylate → Methyl 5-[3-fluoro-4-(trifluoromethyl)phenyl]nicotinate
Reaction equation
[Br:21][c:22]1[cH:23][n:24][cH:25][c:26]([C:27](=[O:28])[O:29][CH3:30])[cH:31]1.[F:1][c:2]1[cH:3][c:4]([B:12]2[O:13][C:14]([CH3:15])([CH3:16])[C:17]([CH3:18])([CH3:19])[O:20]2)[cH:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11]>>[F:1][c:2]1[cH:3][c:4](-[c:22]2[cH:23][n:24][cH:25][c:26]([C:27](=[O:28])[O:29][CH3:30])[cH:31]2)[cH:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11]Participants
3
Sources & evidence
- ORD record
- ord-28496db319f044a4bb45377a29c42581
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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