Potassium Cation → Ethyl 1-(4-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)-2,7-naphthyridine-3-carboxylate

HRID 1224072Notes

Reaction equation

HRID 1224072 reaction equation
[CH3:47][C:48]([OH:49])([CH3:50])[CH3:51].[Cl:1][c:2]1[n:3][c:4]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[cH:5][c:6]2[cH:7][cH:8][n:9][cH:10][c:11]12.[Cl:24][c:25]1[c:26]([C:32](=[O:33])[NH:34][CH:35]2[CH2:36][CH2:37][NH2+:38][CH2:39][CH2:40]2)[nH:27][c:28]([CH3:31])[c:29]1[Cl:30].[F:17][C:18]([F:19])([F:20])[C:21]([O-:22])=[O:23].[K+:41].[K+:42].[O-:43][C:44]([O-:45])=[O:46]>>[c:2]1([N:38]2[CH2:37][CH2:36][CH:35]([NH:34][C:32]([c:26]3[c:25]([Cl:24])[c:29]([Cl:30])[c:28]([CH3:31])[nH:27]3)=[O:33])[CH2:40][CH2:39]2)[n:3][c:4]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[cH:5][c:6]2[cH:7][cH:8][n:9][cH:10][c:11]12

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 6386tert-ButanolHCID 19660Carbonate IonHCID 84468TrifluoroacetateHCID 57947675Ethyl 1-chloro-2,7-naphthyridine-3-carboxylateHCID 178433657HCID 178433657, compound

Product 1

HCID 68579568Ethyl 1-(4-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)-2,7-naphthyridine-3-carboxylate

Sources & evidence

ORD record
ord-7cd70f04729242799ad5a0f48ae425be
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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