1,4-Dioxane → 2-(1-((2-(imidazo[1,2-a]pyridin-5-yl)-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperidin-4-yl)propan-2-ol
Reaction equation
[Br:41][c:42]1[cH:43][cH:44][cH:45][c:46]2[n:47]1[cH:48][cH:49][n:50]2.[CH3:1][n:2]1[c:3]2[n:4][c:5]([Sn:28]([CH2:29][CH2:30][CH2:31][CH3:32])([CH2:33][CH2:34][CH2:35][CH3:36])[CH2:37][CH2:38][CH2:39][CH3:40])[n:6][c:7]([N:22]3[CH2:23][CH2:24][O:25][CH2:26][CH2:27]3)[c:8]2[n:9][c:10]1[CH2:11][N:12]1[CH2:13][CH2:14][CH:15]([C:18]([CH3:19])([CH3:20])[OH:21])[CH2:16][CH2:17]1.[Cu+:65].[O:51]1[CH2:52][CH2:53][O:54][CH2:55][CH2:56]1.[cH:66]1[cH:67][cH:68][c:69]([P:70]([Pd:71]([P:72]([c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)([c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)[c:85]2[cH:86][cH:87][cH:88][cH:89][cH:90]2)([P:91]([c:92]2[cH:93][cH:94][cH:95][cH:96][cH:97]2)([c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)[c:104]2[cH:105][cH:106][cH:107][cH:108][cH:109]2)[P:110]([c:111]2[cH:112][cH:113][cH:114][cH:115][cH:116]2)([c:117]2[cH:118][cH:119][cH:120][cH:121][cH:122]2)[c:123]2[cH:124][cH:125][cH:126][cH:127][cH:128]2)([c:129]2[cH:130][cH:131][cH:132][cH:133][cH:134]2)[c:135]2[cH:136][cH:137][cH:138][cH:139][cH:140]2)[cH:141][cH:142]1.[s:57]1[cH:58][cH:59][cH:60][c:61]1[C:62]([O-:63])=[O:64]>>[CH3:1][n:2]1[c:3]2[n:4][c:5](-[c:42]3[cH:43][cH:44][cH:45][c:46]4[n:47]3[cH:48][cH:49][n:50]4)[n:6][c:7]([N:22]3[CH2:23][CH2:24][O:25][CH2:26][CH2:27]3)[c:8]2[n:9][c:10]1[CH2:11][N:12]1[CH2:13][CH2:14][CH:15]([C:18]([CH3:19])([CH3:20])[OH:21])[CH2:16][CH2:17]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-200428490dad41f7a2cd391d0cd02691
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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