Sulfuryl chloride → 5-bromo-3-hydroxy-3-(2-methoxy-5-methylphenyl)-1-{[4-methoxy-2-(trifluoromethoxy)phenyl]sulfonyl}-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[NH:8][C:9](=[O:21])[C:10]2([c:11]1[c:12]([O:18][CH3:19])[cH:13][cH:14][c:15]([CH3:17])[cH:16]1)[OH:20].[CH3:27][O:28][c:29]1[cH:30][c:31]([O:35][C:36]([F:37])([F:38])[F:39])[cH:32][cH:33][cH:34]1.[S:22](=[O:23])(=[O:24])([Cl:25])[Cl:26]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[N:8]([S:22](=[O:23])(=[O:24])[c:32]1[c:31]([O:35][C:36]([F:37])([F:38])[F:39])[cH:30][c:29]([O:28][CH3:27])[cH:34][cH:33]1)[C:9](=[O:21])[C:10]2([c:11]1[c:12]([O:18][CH3:19])[cH:13][cH:14][c:15]([CH3:17])[cH:16]1)[OH:20]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-314b4ea3167c470c877f454168bf339a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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