Methanol → (+/-)-1-[3,5-Bis(trifluoromethyl)benzoyl]-2-(phenylmethyl)-4-(1-piperazinyl)piperidine

HRID 1224272Notes

Reaction equation

HRID 1224272 reaction equation
[CH3:43][OH:44].[F:1][C:2]([c:3]1[cH:4][c:5]([C:6](=[O:7])[N:8]2[CH:9]([CH2:27][c:28]3[cH:29][cH:30][cH:31][cH:32][cH:33]3)[CH2:10][CH:11]([N:14]3[CH2:15][CH2:16][N:17]([CH2:20][c:21]4[cH:22][cH:23][cH:24][cH:25][cH:26]4)[CH2:18][CH2:19]3)[CH2:12][CH2:13]2)[cH:34][c:35]([C:37]([F:38])([F:39])[F:40])[cH:36]1)([F:41])[F:42]>>[F:1][C:2]([c:3]1[cH:4][c:5]([C:6](=[O:7])[N:8]2[CH:9]([CH2:27][c:28]3[cH:29][cH:30][cH:31][cH:32][cH:33]3)[CH2:10][CH:11]([N:14]3[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]3)[CH2:12][CH2:13]2)[cH:34][c:35]([C:37]([F:38])([F:39])[F:40])[cH:36]1)([F:41])[F:42]

Participants

3

Reactant 2

HCID 887MethanolHCID 18630815[2-Benzyl-4-(4-benzylpiperazin-1-yl)piperidin-1-yl]-[3,5-bis(trifluoromethyl)phenyl]methanone

Product 1

HCID 18630855(+/-)-1-[3,5-Bis(trifluoromethyl)benzoyl]-2-(phenylmethyl)-4-(1-piperazinyl)piperidine

Sources & evidence

ORD record
ord-3bf926ef21074a418b434c3fbfa25082
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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