Methanol → benzyl N-[[(3S,4R)-4-hydroxypyrrolidin-3-yl]methyl]carbamate

HRID 1224288Notes

Reaction equation

HRID 1224288 reaction equation
[CH3:51][OH:52].[Cl:53][CH2:54][Cl:55].[OH:1][CH:2]1[CH2:3][N:4]([C:19]([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[CH2:5][CH:6]1[CH2:7][NH:8][C:9](=[O:10])[O:11][CH2:12][c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1.[OH:26][CH:27]1[CH:28]([CH2:29][NH:30][C:31]([O:32][CH2:33][c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)=[O:40])[CH2:41][N:42]([C:43]([O:44][C:45]([CH3:46])([CH3:47])[CH3:48])=[O:49])[CH2:50]1>>[OH:1][CH:2]1[CH2:3][NH:4][CH2:5][CH:6]1[CH2:7][NH:8][C:9](=[O:10])[O:11][CH2:12][c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1

Participants

4

Reactant 3

HCID 887MethanolHCID 6344DichloromethaneHCID 57415726tert-Butyl 3-((((benzyloxy)carbonyl)amino)methyl)-4-hydroxypyrrolidine-1-carboxylate2×

Product 1

HCID 19691312benzyl N-[[(3S,4R)-4-hydroxypyrrolidin-3-yl]methyl]carbamate

Sources & evidence

ORD record
ord-81b5360a3e114a08b58d8b2c0323a67c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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