tert-butyl 4-(4-methoxyanilino)tetrahydro-1(2H)-pyridinecarboxylate → 1-(tert-butoxycarbonyl)-4-[N-(4-methoxyphenyl)-N-[[3-(3,4,5-trimethoxyphenyl) pyridin-5-yl]methyl]amino]piperidine

HRID 122430Notes

Reaction equation

HRID 122430 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([NH:9][CH:10]2[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[cH:7][cH:8]1.[Cl:23][CH2:24][c:25]1[cH:26][c:27](-[c:31]2[cH:32][c:33]([O:41][CH3:42])[c:34]([O:39][CH3:40])[c:35]([O:37][CH3:38])[cH:36]2)[cH:28][n:29][cH:30]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([N:9]([CH:10]2[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[CH2:24][c:25]2[cH:26][c:27](-[c:31]3[cH:32][c:33]([O:41][CH3:42])[c:34]([O:39][CH3:40])[c:35]([O:37][CH3:38])[cH:36]3)[cH:28][n:29][cH:30]2)[cH:7][cH:8]1

Participants

3

Reactant 2

HCID 2776119tert-butyl 4-(4-methoxyanilino)tetrahydro-1(2H)-pyridinecarboxylateHCID 225578743-Chloromethyl-5-(3,4,5-trimethoxyphenyl)pyridine

Product 1

HCID 225577881-(tert-butoxycarbonyl)-4-[N-(4-methoxyphenyl)-N-[[3-(3,4,5-trimethoxyphenyl) pyridin-5-yl]methyl]amino]piperidine

Sources & evidence

ORD record
ord-311e471a435f4e089fec3263803db5aa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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