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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1224487Generated: October 25, 2026

Water → 6-Amino-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-chloropyrimidine-4-carboxylic acid methyl ester

https://huagongshe.com/reaction/1224487

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantFluoride IonHCID 28179—
ReactantCesium cationHCID 104967—
ReactantMethyl 6-amino-2,5-dichloropyrimidine-4-carboxylateHCID 312630—
Reactant2-(4-Chloro-2-fluoro-3-methoxyphenyl)-1,3,2-dioxaborinaneHCID 57782419—
Product6-Amino-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-chloropyrimidine-4-carboxylic acid methyl esterHCID 16656801—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-6e8e3e82f03d4ee48e82d3bb39fcd54a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)