3-iodo-1-[4-(4-methylpiperazino)cyclohexyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine → HCID 20817045, compound

HRID 1224547Notes

Reaction equation

HRID 1224547 reaction equation
[CH3:25][C:26]1([CH3:27])[C:28]([CH3:29])([CH3:30])[O:31][B:32]([c:33]2[cH:34][cH:35][c:36](-[c:39]3[n:40][c:41]4[n:42]([cH:43][cH:44][cH:45][cH:46]4)[cH:47]3)[cH:37][cH:38]2)[O:48]1.[I:1][c:2]1[n:3][n:4]([CH:12]2[CH2:13][CH2:14][CH:15]([N:18]3[CH2:19][CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]3)[CH2:16][CH2:17]2)[c:5]2[n:6][cH:7][n:8][c:9]([NH2:11])[c:10]12.[NH2:49][c:50]1[n:51][cH:52][n:53][c:54]2[n:55]([CH:56]3[CH2:57][CH2:58][CH:59]([N:60]4[CH2:61][CH2:62][N:63]([CH3:64])[CH2:65][CH2:66]4)[CH2:67][CH2:68]3)[n:69][c:70](-[c:71]3[cH:72][cH:73][c:74]([NH:75][c:76]4[o:77][c:78]5[cH:79][cH:80][cH:81][cH:82][c:83]5[n:84]4)[c:85]([F:86])[cH:87]3)[c:88]12>>[c:2]1(-[c:33]2[cH:34][cH:35][c:36](-[c:39]3[n:40][c:41]4[n:42]([cH:43][cH:44][cH:45][cH:46]4)[cH:47]3)[cH:37][cH:38]2)[n:3][n:4]([CH:12]2[CH2:13][CH2:14][CH:15]([N:18]3[CH2:19][CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]3)[CH2:16][CH2:17]2)[c:5]2[n:6][cH:7][n:8][c:9]([NH2:11])[c:10]12

Participants

4

Reactant 3

HCID 208170473-iodo-1-[4-(4-methylpiperazino)cyclohexyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amineHCID 20817079Trans-N2-(4-{4-amino-1-[4-(4-methylpiperazino)cyclohexyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}-2-fluorophenyl)-1,3-benzoxazol-2-amineHCID 223467412-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)imidazo[1,2-a]pyridine

Product 1

HCID 20817045HCID 20817045, compound

Sources & evidence

ORD record
ord-db6ebdca58e94baf84df68a99fa0894d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…