Ethanol → Zomepirac

HRID 1224573Notes

Reaction equation

HRID 1224573 reaction equation
[CH3:23][CH2:24][OH:25].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[c:8]2[c:9]([CH3:20])[cH:10][c:11]([CH2:14][C:15](=[O:16])[O:17][CH2:18][CH3:19])[n:12]2[CH3:13])[cH:21][cH:22]1.[Na+:27].[OH-:26].[OH2:28]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[c:8]2[c:9]([CH3:20])[cH:10][c:11]([CH2:14][C:15](=[O:16])[OH:17])[n:12]2[CH3:13])[cH:21][cH:22]1

Participants

6

Reactant 5

HCID 702EthanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 118463ethyl 5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetate

Product 1

HCID 5733Zomepirac

Sources & evidence

ORD record
ord-355bb9e041f644218e46de4143e1a8e8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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