4-[6-Amino-5-(2,6-dichloro-benzyloxy)-pyridin-3-yl]-benzoic acid → 4-[6-Amino-5-(2,6-dichloro-benzyloxy)-pyridin-3-yl]-N-(2-hydroxy-3-pyrrolidin-1-yl-propyl)-benzamide

HRID 122462Notes

Reaction equation

HRID 122462 reaction equation
[NH2:1][c:2]1[c:3]([O:17][CH2:18][c:19]2[c:20]([Cl:26])[cH:21][cH:22][cH:23][c:24]2[Cl:25])[cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([C:12](=[O:13])[OH:14])[cH:15][cH:16]2)[cH:6][n:7]1.[NH2:27][CH2:28][CH:29]([CH2:30][N:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1)[OH:36]>>[NH2:1][c:2]1[c:3]([O:17][CH2:18][c:19]2[c:20]([Cl:26])[cH:21][cH:22][cH:23][c:24]2[Cl:25])[cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([C:12](=[O:13])[NH:27][CH2:28][CH:29]([CH2:30][N:31]3[CH2:32][CH2:33][CH2:34][CH2:35]3)[OH:36])[cH:15][cH:16]2)[cH:6][n:7]1

Participants

3

Reactant 2

HCID 103181294-[6-Amino-5-(2,6-dichloro-benzyloxy)-pyridin-3-yl]-benzoic acidHCID 121749931-Amino-3-(pyrrolidin-1-yl)propan-2-ol

Product 1

HCID 99839974-[6-Amino-5-(2,6-dichloro-benzyloxy)-pyridin-3-yl]-N-(2-hydroxy-3-pyrrolidin-1-yl-propyl)-benzamide

Sources & evidence

ORD record
ord-40ceb62bff184582a7fe6ed6e7a06338
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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