5-Bromo-2-chloroanisole → (4-Chloro-3-methoxy-phenyl)-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-amine

HRID 122474Notes

Reaction equation

HRID 122474 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([Cl:10])[c:6]([O:8][CH3:9])[cH:7]1.[F:11][C:12]([c:13]1[cH:14][cH:15][c:16]([CH2:19][CH2:20][NH2:21])[n:17][cH:18]1)([F:22])[F:23]>>[c:2]1([NH:21][CH2:20][CH2:19][c:16]2[cH:15][cH:14][c:13]([C:12]([F:11])([F:22])[F:23])[cH:18][n:17]2)[cH:3][cH:4][c:5]([Cl:10])[c:6]([O:8][CH3:9])[cH:7]1

Participants

3

Reactant 2

HCID 27695675-Bromo-2-chloroanisoleHCID 180713442-(5-Trifluoromethyl-pyridin-2-YL)-ethylamine

Product 1

HCID 58007553(4-Chloro-3-methoxy-phenyl)-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-amine

Sources & evidence

ORD record
ord-364c502799f047cd921366d2f1a54f6a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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