Dichloromethane → [4-(4-Dimethylamino-quinazolin-2-ylamino)-phenyl]-carbamic acid tert-butyl ester

HRID 1224869Notes

Reaction equation

HRID 1224869 reaction equation
[C:15]([CH3:16])([CH3:17])([CH3:18])[O:19][C:20]([NH:21][c:22]1[cH:23][cH:24][c:25]([NH2:28])[cH:26][cH:27]1)=[O:29].[Cl:1][c:2]1[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[c:10]([N:12]([CH3:13])[CH3:14])[n:11]1.[Cl:30][CH2:31][Cl:32]>>[c:2]1([NH:28][c:25]2[cH:24][cH:23][c:22]([NH:21][C:20]([O:19][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:29])[cH:27][cH:26]2)[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[c:10]([N:12]([CH3:13])[CH3:14])[n:11]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 688611tert-Butyl (4-aminophenyl)carbamateHCID 126843422-Chloro-N,N-dimethylquinazolin-4-amine

Product 1

HCID 68846735[4-(4-Dimethylamino-quinazolin-2-ylamino)-phenyl]-carbamic acid tert-butyl ester

Sources & evidence

ORD record
ord-586c61b40c184c4fa00d2b5d1750039d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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