2′-Fluoro-5′-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)[1,1′-biphenyl]-2-carbonitrile → 5'-[7-Acetyl-[1,8]naphthyridin-4-yl]-2'-fluorobiphenyl-2-carbonitrile

HRID 1225158Notes

Reaction equation

HRID 1225158 reaction equation
[Cl:1][c:2]1[c:3]2[cH:4][cH:5][c:6]([C:12]([CH3:13])=[O:14])[n:7][c:8]2[n:9][cH:10][cH:11]1.[F:15][c:16]1[c:17](-[c:31]2[c:32]([C:37]#[N:38])[cH:33][cH:34][cH:35][cH:36]2)[cH:18][c:19]([B:22]2[O:23][C:24]([CH3:25])([CH3:26])[C:27]([CH3:28])([CH3:29])[O:30]2)[cH:20][cH:21]1>>[c:2]1(-[c:19]2[cH:18][c:17](-[c:31]3[c:32]([C:37]#[N:38])[cH:33][cH:34][cH:35][cH:36]3)[c:16]([F:15])[cH:21][cH:20]2)[c:3]2[cH:4][cH:5][c:6]([C:12]([CH3:13])=[O:14])[n:7][c:8]2[n:9][cH:10][cH:11]1

Participants

3

Reactant 2

HCID 117716472′-Fluoro-5′-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)[1,1′-biphenyl]-2-carbonitrileHCID 222853341-(5-chloro-1,8-naphthyridin-2-yl)Ethanone

Product 1

HCID 99254355'-[7-Acetyl-[1,8]naphthyridin-4-yl]-2'-fluorobiphenyl-2-carbonitrile

Sources & evidence

ORD record
ord-3cd117c62bef4998a73b5a3732267c14
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…