Bromide ion → 2-Chloro-5-cyclobutylpyrimidine

HRID 1225273Notes

Reaction equation

HRID 1225273 reaction equation
[Br-:9].[Br:1][c:2]1[cH:3][n:4][c:5]([Cl:8])[n:6][cH:7]1.[CH:10]1([Zn+:14])[CH2:11][CH2:12][CH2:13]1.[Cl:15][CH2:16][Cl:17]>>[c:2]1([CH:10]2[CH2:11][CH2:12][CH2:13]2)[cH:3][n:4][c:5]([Cl:8])[n:6][cH:7]1

Participants

5

Reactant 4

HCID 259Bromide ionHCID 6344DichloromethaneHCID 6066655-Bromo-2-chloropyrimidineHCID 178528062HCID 178528062, compound

Product 1

HCID 665200122-Chloro-5-cyclobutylpyrimidine

Sources & evidence

ORD record
ord-8b1bae3bfdc34131b3cd676c8706b12b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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