Methanol → Tert-butyl 4-amino-3-propan-2-yloxypiperidine-1-carboxylate

HRID 1225415Notes

Reaction equation

HRID 1225415 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][CH:9]1[CH:10]([O:22][CH:23]([CH3:24])[CH3:25])[CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]1.[CH3:26][OH:27].[OH-:28].[OH-:30].[Pd+2:29]>>[NH2:8][CH:9]1[CH:10]([O:22][CH:23]([CH3:24])[CH3:25])[CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]1

Participants

5

Reactant 4

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 68415755Tert-butyl 4-(benzylamino)-3-propan-2-yloxypiperidine-1-carboxylate

Product 1

HCID 68415663Tert-butyl 4-amino-3-propan-2-yloxypiperidine-1-carboxylate

Sources & evidence

ORD record
ord-193c84c3a3214a6785d596aa54c8c0f1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…