HRID1225485

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8028

Tetrahydrofuran

C4H8O

HCID81184

1,8-Diazabicyclo[5.4.0]undec-7-ene

C9H16N2

HCID81430

N-(3-Methoxyphenyl)piperazine

C11H16N2O

HCID69244192

未命名化合物

PRODUCTS

生成物

结构：COc1cccc(N2CCN(C(=O)Nc3nc4cc(F)c(F)cc4nc3OC)CC2)c1

HCID69243616

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b7065d00ce2445e886349319da943bd1
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (5/10)

反应 SMILES

[CH2:35]1[CH2:36][CH2:37][C:38]2=[N:43][CH2:42][CH2:41][CH2:40][N:39]2[CH2:44][CH2:45]1.[CH3:21][O:22][c:23]1[cH:24][c:25]([N:29]2[CH2:30][CH2:31][NH:32][CH2:33][CH2:34]2)[cH:26][cH:27][cH:28]1.[F:1][c:2]1[cH:3][c:4]2[n:5][c:6]([NH:15][C:16]([O:17][CH2:18][CH3:19])=[O:20])[c:7]([O:13][CH3:14])[n:8][c:9]2[cH:10][c:11]1[F:12].[O:46]1[CH2:47][CH2:48][CH2:49][CH2:50]1>>[F:1][c:2]1[cH:3][c:4]2[n:5][c:6]([NH:15][C:16](=[O:20])[N:32]3[CH2:31][CH2:30][N:29]([c:25]4[cH:24][c:23]([O:22][CH3:21])[cH:28][cH:27][cH:26]4)[CH2:34][CH2:33]3)[c:7]([O:13][CH3:14])[n:8][c:9]2[cH:10][c:11]1[F:12]