Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1225618Generated: October 31, 2026

Water → 4'-[2-(2-Chloro-4-trifluoromethanesulfonyloxy-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-carboxylic acid ethyl ester

https://huagongshe.com/reaction/1225618

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantN-methyl-2-pyrrolidoneHCID 13387—
ReactantEthyl 4-piperidinecarboxylateHCID 70770—
ReactantTrifluoro-methanesulfonic acid 3-chloro-4-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-phenyl esterHCID 86629107—
Product4'-[2-(2-Chloro-4-trifluoromethanesulfonyloxy-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-carboxylic acid ethyl esterHCID 86629108—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-976313c5a2584b06b3b3448265aeac6d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)