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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1225639Generated: October 25, 2026

Tetrahydrofuran → 6-chloro-4-(4-fluorophenyl)-4-hydroxy-3-(2,2,2-trifluoroethyl)-3,4-dihydroquinazolin-2(1H)-one

https://huagongshe.com/reaction/1225639

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantEthanamine, 2,2,2-trifluoro-HCID 9773—
ReactantN-(4-chloro-2-(4-fluorobenzoyl)phenyl)-1H-imidazole-1-carboxamideHCID 59346602—
Product6-chloro-4-(4-fluorophenyl)-4-hydroxy-3-(2,2,2-trifluoroethyl)-3,4-dihydroquinazolin-2(1H)-oneHCID 59346598—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-35b8f0be291f467e93071f210e28afa5
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)