2,5-dichloro-N-(2-((1-methylethyl)sulfonyl)phenyl)-4-pyrimidinamine → 2-(7-{5-Chloro-4-[2-(propane-2-sulfonyl)-phenylamino]-pyrimidin-2-ylamino}-8-methoxy-1,2,4,5-tetrahydro-3-benzazepin-3-yl)-1-(4-methyl-piperazin-1-yl)-ethanone
Reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:21])[c:6]([NH:8][c:9]2[c:10]([S:15](=[O:16])(=[O:17])[CH:18]([CH3:19])[CH3:20])[cH:11][cH:12][cH:13][cH:14]2)[n:7]1.[NH2:22][c:23]1[cH:24][c:25]2[c:26]([cH:42][c:43]1[O:44][CH3:45])[CH2:27][CH2:28][N:29]([CH2:32][C:33](=[O:34])[N:35]1[CH2:36][CH2:37][N:38]([CH3:41])[CH2:39][CH2:40]1)[CH2:30][CH2:31]2>>[c:2]1([NH:22][c:23]2[cH:24][c:25]3[c:26]([cH:42][c:43]2[O:44][CH3:45])[CH2:27][CH2:28][N:29]([CH2:32][C:33](=[O:34])[N:35]2[CH2:36][CH2:37][N:38]([CH3:41])[CH2:39][CH2:40]2)[CH2:30][CH2:31]3)[n:3][cH:4][c:5]([Cl:21])[c:6]([NH:8][c:9]2[c:10]([S:15](=[O:16])(=[O:17])[CH:18]([CH3:19])[CH3:20])[cH:11][cH:12][cH:13][cH:14]2)[n:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-82e87f65f8a84500a2581e88f3aa17e1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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