Dimethyl Sulfoxide → 3-Bromo-6-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazine
Reaction equation
[Br:14][c:15]1[cH:16][n:17][c:18]2[n:19]1[n:20][c:21]([Cl:24])[cH:22][cH:23]2.[CH3:30][S:31]([CH3:32])=[O:33].[Cl:27][CH2:28][Cl:29].[F-:25].[F:1][c:2]1[c:3]([CH:9]2[NH:10][CH2:11][CH2:12][CH2:13]2)[cH:4][c:5]([F:8])[cH:6][cH:7]1.[K+:26]>>[F:1][c:2]1[c:3]([CH:9]2[N:10]([c:21]3[n:20][n:19]4[c:15]([Br:14])[cH:16][n:17][c:18]4[cH:23][cH:22]3)[CH2:11][CH2:12][CH2:13]2)[cH:4][c:5]([F:8])[cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-8787e8d054bc4a99b118951128b3a297
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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