2-Chloro-7-(trifluoromethyl)quinoxaline → [5-Methyl-2-(trifluoromethyl)phenyl]-[3-[[7-(trifluoromethyl)quinoxalin-2-yl]amino]pyrrolidin-1-yl]methanone

HRID 1226240Notes

Reaction equation

HRID 1226240 reaction equation
[Cl:1][c:2]1[n:3][c:4]2[cH:5][c:6]([C:12]([F:13])([F:14])[F:15])[cH:7][cH:8][c:9]2[n:10][cH:11]1.[NH2:16][CH:17]1[CH2:18][N:19]([C:22](=[O:23])[c:24]2[c:25]([C:31]([F:32])([F:33])[F:34])[cH:26][cH:27][c:28]([CH3:30])[cH:29]2)[CH2:20][CH2:21]1>>[c:2]1([NH:16][CH:17]2[CH2:18][N:19]([C:22](=[O:23])[c:24]3[c:25]([C:31]([F:32])([F:33])[F:34])[cH:26][cH:27][c:28]([CH3:30])[cH:29]3)[CH2:20][CH2:21]2)[n:3][c:4]2[cH:5][c:6]([C:12]([F:13])([F:14])[F:15])[cH:7][cH:8][c:9]2[n:10][cH:11]1

Participants

3

Reactant 2

HCID 213131612-Chloro-7-(trifluoromethyl)quinoxalineHCID 68731648(3-Aminopyrrolidin-1-yl)-[5-methyl-2-(trifluoromethyl)phenyl]methanone

Product 1

HCID 87563747[5-Methyl-2-(trifluoromethyl)phenyl]-[3-[[7-(trifluoromethyl)quinoxalin-2-yl]amino]pyrrolidin-1-yl]methanone

Sources & evidence

ORD record
ord-5237d699f562428c9abf5f10c335b1cd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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