Pyridine → tert-Butyl 5-(4-(4-bromophenyl)butanamido)-2-(ethylsulfonyl)benzylcarbamate

HRID 1226256Notes

Reaction equation

HRID 1226256 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH2:9][CH2:10][C:11](=[O:12])[NH:13][c:14]2[cH:15][c:16]([C:25]#[N:26])[c:17]([S:20](=[O:21])(=[O:22])[CH2:23][CH3:24])[cH:18][cH:19]2)[cH:6][cH:7]1.[Br:48][c:49]1[cH:50][cH:51][c:52]([CH2:53][CH2:54][CH2:55][C:56]([OH:57])=[O:58])[cH:59][cH:60]1.[NH2:27][c:28]1[cH:29][cH:30][c:31]([S:32]([CH2:33][CH3:34])(=[O:42])=[O:43])[c:44]([CH2:46][NH:47][C:35]([O:36][C:37]([CH3:38])([CH3:39])[CH3:40])=[O:41])[cH:45]1.[cH:61]1[cH:62][cH:63][n:64][cH:65][cH:66]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH2:9][CH2:10][C:11](=[O:12])[NH:13][c:14]2[cH:15][c:16]([CH2:25][NH:26][C:35]([O:36][C:37]([CH3:38])([CH3:39])[CH3:40])=[O:41])[c:17]([S:20](=[O:21])(=[O:22])[CH2:23][CH3:24])[cH:18][cH:19]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 2527324-(4-Bromophenyl)butyric AcidHCID 57842618HCID 57842618, compoundHCID 578426674-(4-Bromophenyl)-N-(3-cyano-4-(ethylsulfonyl)phenyl)butanamide

Product 1

HCID 57842758tert-Butyl 5-(4-(4-bromophenyl)butanamido)-2-(ethylsulfonyl)benzylcarbamate

Sources & evidence

ORD record
ord-d6ace4a1fc114b15a259aa6dccded6da
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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