1-(Bromomethyl)-3-(trifluoromethyl)benzene → 3-(2,3-Dihydro-benzo[1,4]dioxine-6-carbonyl)-1-(3-trifluoromethyl-benzyl)-1H-quinolin-4-one
Reaction equation
[Br:24][CH2:25][c:26]1[cH:27][c:28]([C:32]([F:33])([F:34])[F:35])[cH:29][cH:30][cH:31]1.[O:1]1[CH2:2][CH2:3][O:4][c:5]2[c:6]1[cH:7][cH:8][c:9]([C:11](=[O:12])[c:13]1[cH:14][nH:15][c:16]3[cH:17][cH:18][cH:19][cH:20][c:21]3[c:22]1=[O:23])[cH:10]2>>[O:1]1[CH2:2][CH2:3][O:4][c:5]2[c:6]1[cH:7][cH:8][c:9]([C:11](=[O:12])[c:13]1[cH:14][n:15]([CH2:25][c:26]3[cH:27][c:28]([C:32]([F:33])([F:34])[F:35])[cH:29][cH:30][cH:31]3)[c:16]3[cH:17][cH:18][cH:19][cH:20][c:21]3[c:22]1=[O:23])[cH:10]2Participants
3
Sources & evidence
- ORD record
- ord-ba07e9a61db14c28a191499f3cf7fae6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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