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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1227030Generated: November 2, 2026

Tetrahydrofuran → tert-butyl 2-[3-[2-[[3-(2,4-dichlorophenyl)-2-(2-hydroxycyclohexyl)-1-oxo-3,4-dihydroisoquinoline-4-carbonyl]amino]ethyl]phenoxy]propanoate

https://huagongshe.com/reaction/1227030

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
ReactantTriphenylphosphineHCID 11776—
Reactantethyl N-ethoxycarbonyliminocarbamateHCID 220568—
ReactantTert-butyl 2-hydroxypropanoateHCID 3604460—
Reactant(3RS,4RS)-3-(2,4-dichlorophenyl)-2-[(1SR,2SR)-2-hydroxycyclohexyl]-N-[2-(3-hydroxyphenyl)ethyl]-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamideHCID 68449574—
Producttert-butyl 2-[3-[2-[[3-(2,4-dichlorophenyl)-2-(2-hydroxycyclohexyl)-1-oxo-3,4-dihydroisoquinoline-4-carbonyl]amino]ethyl]phenoxy]propanoateHCID 178466526—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-07f0b9d13e79405ab153b143f59b9197
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)