反应详情

6-(2-Ethylaminopyrimidin-4-yl)-3-oxo-2,3-dihydropyridazine-4-carboxylic acid (2-amino-4-chlorophenyl)amide (50 mg) are stirred in 1 ml of glacial acetic acid at 100° C. for 3 hours. After cooling, the precipitate is filtered off with suction, stirred with aqueous sodium bicarbonate solution and again filtered off with suction, washed with water and dried in vacuo.

1. temperatureAfter cooling
2. filtrationthe precipitate is filtered off with suction
3. filtrationagain filtered off with suction
4. washwashed with water
5. customdried in vacuo