Toluene → 2,6-Difluorobenzene-1-carbothioamide

HRID 1227309Notes

Reaction equation

HRID 1227309 reaction equation
[CH3:12][O:13][c:14]1[cH:15][cH:16][c:17]([P:18]2(=[S:21])[S:19][P:20]([c:22]3[cH:23][cH:24][c:25]([O:26][CH3:27])[cH:28][cH:29]3)(=[S:30])[S:31]2)[cH:32][cH:33]1.[CH3:34][c:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1.[F:1][c:2]1[c:3]([C:4](=[O:5])[NH2:6])[c:7]([F:11])[cH:8][cH:9][cH:10]1>>[F:1][c:2]1[c:3]([C:4]([NH2:6])=[S:21])[c:7]([F:11])[cH:8][cH:9][cH:10]1

Participants

4

Reactant 3

HCID 1140TolueneHCID 874392,6-DifluorobenzamideHCID 87949Lawesson's reagent

Product 1

HCID 126832122,6-Difluorobenzene-1-carbothioamide

Sources & evidence

ORD record
ord-48aa2e41291645b9ae20baa6f4a8248d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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