Sodium ion → 2-Oxazolidinone, 5-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-iodo-5-(trifluoromethyl)phenyl]methyl]-4-methyl-, (4S,5R)-

HRID 1227312Notes

Reaction equation

HRID 1227312 reaction equation
[Br:24][CH2:25][c:26]1[c:27]([I:36])[cH:28][cH:29][c:30]([C:32]([F:33])([F:34])[F:35])[cH:31]1.[F:1][C:2]([c:3]1[cH:4][c:5]([CH:13]2[CH:14]([CH3:19])[NH:15][C:16](=[O:18])[O:17]2)[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:20])[F:21].[H-:23].[Na+:22]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH:13]2[CH:14]([CH3:19])[N:15]([CH2:25][c:26]3[c:27]([I:36])[cH:28][cH:29][c:30]([C:32]([F:33])([F:34])[F:35])[cH:31]3)[C:16](=[O:18])[O:17]2)[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:20])[F:21]

Participants

5

Reactant 4

HCID 923Sodium ionHCID 166653HydrideHCID 184515342-(Bromomethyl)-1-iodo-4-(trifluoromethyl)benzeneHCID 591352455-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one

Product 1

HCID 760248592-Oxazolidinone, 5-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-iodo-5-(trifluoromethyl)phenyl]methyl]-4-methyl-, (4S,5R)-

Sources & evidence

ORD record
ord-b859c895d9134be3b1e5526440c74ed4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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