Methyl Ethyl Ketone → (+)-2-(2-Bromo-ethyl)-10-(3-hydroxy-phenyl)-6-methoxy-3a-methyl-3a,4,9,10-tetrahydro-2,9,10a-triaza-cyclopenta[b]fluorene-1,3-dione

HRID 1227626Notes

Reaction equation

HRID 1227626 reaction equation
[Br:28][CH2:29][CH2:30][N:31]=[C:32]=[O:33].[CH3:1][O:2][C:3](=[O:4])[C:5]1([CH3:27])[NH:6][CH:7]([c:20]2[cH:21][c:22]([OH:26])[cH:23][cH:24][cH:25]2)[c:8]2[nH:9][c:10]3[cH:11][cH:12][c:13]([O:18][CH3:19])[cH:14][c:15]3[c:16]2[CH2:17]1.[CH3:34][C:35](=[O:36])[CH2:37][CH3:38]>>[C:3]1(=[O:4])[C:5]2([CH3:27])[N:6]([CH:7]([c:20]3[cH:21][c:22]([OH:26])[cH:23][cH:24][cH:25]3)[c:8]3[nH:9][c:10]4[cH:11][cH:12][c:13]([O:18][CH3:19])[cH:14][c:15]4[c:16]3[CH2:17]2)[C:32](=[O:33])[N:31]1[CH2:30][CH2:29][Br:28]

Participants

4

Reactant 3

HCID 6569Methyl Ethyl KetoneHCID 42559572-Bromoethyl isocyanateHCID 68851536(1RS,3RS)-1-(3-hydroxy-phenyl)-6-methoxy-3-methyl-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid methyl ester

Product 1

HCID 68939448(+)-2-(2-Bromo-ethyl)-10-(3-hydroxy-phenyl)-6-methoxy-3a-methyl-3a,4,9,10-tetrahydro-2,9,10a-triaza-cyclopenta[b]fluorene-1,3-dione

Sources & evidence

ORD record
ord-4cdf3cd004dd48378330276c9ebe0ae4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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