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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1227648Generated: October 26, 2026

Bicarbonate Ion → Methyl 4-bromo-5-[3-[[1-[(2-methylphenyl)methylsulfonyl]piperidin-4-yl]amino]phenyl]-3-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]thiophene-2-carboxylate

https://huagongshe.com/reaction/1227648

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantDichloromethaneHCID 6344—
Reactant(2-methylphenyl)methanesulfonyl ChlorideHCID 2760661—
ReactantMethyl 4-bromo-3-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]-5-[3-(piperidin-4-ylamino)phenyl]thiophene-2-carboxylateHCID 17758124—
ProductMethyl 4-bromo-5-[3-[[1-[(2-methylphenyl)methylsulfonyl]piperidin-4-yl]amino]phenyl]-3-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]thiophene-2-carboxylateHCID 17758678—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-4c7ad0dc7b5b44d2a65b74349d184b3c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)