2-Fluorophenylboronic acid → 4-(2,6-Difluoro-phenylamino)-6-(2-fluoro-phenyl)-2-methylsulfanyl-pyrimidine-5-carbaldehyde

HRID 1227712Notes

Reaction equation

HRID 1227712 reaction equation
[Cl:1][c:2]1[n:3][c:4]([S:19][CH3:20])[n:5][c:6]([NH:10][c:11]2[c:12]([F:18])[cH:13][cH:14][cH:15][c:16]2[F:17])[c:7]1[CH:8]=[O:9].[F:21][c:22]1[c:23]([B:28]([OH:29])[OH:30])[cH:24][cH:25][cH:26][cH:27]1>>[c:2]1(-[c:23]2[c:22]([F:21])[cH:27][cH:26][cH:25][cH:24]2)[n:3][c:4]([S:19][CH3:20])[n:5][c:6]([NH:10][c:11]2[c:12]([F:18])[cH:13][cH:14][cH:15][c:16]2[F:17])[c:7]1[CH:8]=[O:9]

Participants

3

Reactant 2

HCID 27343542-Fluorophenylboronic acidHCID 99447374-Chloro-6-((2,6-difluorophenyl)amino)-2-(methylthio)pyrimidine-5-carbaldehyde

Product 1

HCID 102928404-(2,6-Difluoro-phenylamino)-6-(2-fluoro-phenyl)-2-methylsulfanyl-pyrimidine-5-carbaldehyde

Sources & evidence

ORD record
ord-feb2b69803fc4192a0bb9652bf37af0e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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