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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1228350Generated: October 25, 2026

Water → 6-Amino-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-methoxypyrimidine-4-carboxylic acid methyl ester

https://huagongshe.com/reaction/1228350

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantEthyl AcetateHCID 8857—
ReactantFluoride IonHCID 28179—
ReactantCesium cationHCID 104967—
Reactant4-Chloro-2-fluoro-3-methoxyphenylboronic acidHCID 44129706—
ReactantMethyl 6-amino-2-chloro-5-methoxypyrimidine-4-carboxylateHCID 52270701—
Product6-Amino-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-methoxypyrimidine-4-carboxylic acid methyl esterHCID 59126928—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-bc86a982648e4618b85251665455b267
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)