Methanol → 3-(5-(Azetidin-1-ylmethyl)-1-methyl-1H-pyrazol-3-ylamino)-5-bromo-1-methylpyridin-2(1H)-one
Reaction equation
[Br:13][c:14]1[c:15](=[O:22])[n:16]([CH3:21])[cH:17][c:18]([Br:20])[cH:19]1.[C:23](=[O:24])([O-:25])[O-:26].[CH2:29]1[O:30][CH2:31][CH2:32][O:33][CH2:34]1.[CH2:93]([Cl:94])[Cl:95].[CH3:91][OH:92].[Cs+:27].[Cs+:28].[N:1]1([CH2:5][c:6]2[cH:7][c:8]([NH2:12])[n:9][n:10]2[CH3:11])[CH2:2][CH2:3][CH2:4]1.[O:37]=[C:38]([CH:39]=[CH:40][c:41]1[cH:42][cH:43][cH:44][cH:45][cH:46]1)[CH:47]=[CH:48][c:49]1[cH:50][cH:51][cH:52][cH:53][cH:54]1.[O:55]=[C:56]([CH:57]=[CH:58][c:59]1[cH:60][cH:61][cH:62][cH:63][cH:64]1)[CH:65]=[CH:66][c:67]1[cH:68][cH:69][cH:70][cH:71][cH:72]1.[O:73]=[C:74]([CH:75]=[CH:76][c:77]1[cH:78][cH:79][cH:80][cH:81][cH:82]1)[CH:83]=[CH:84][c:85]1[cH:86][cH:87][cH:88][cH:89][cH:90]1.[Pd:35].[Pd:36]>>[N:1]1([CH2:5][c:6]2[cH:7][c:8]([NH:12][c:14]3[c:15](=[O:22])[n:16]([CH3:21])[cH:17][c:18]([Br:20])[cH:19]3)[n:9][n:10]2[CH3:11])[CH2:2][CH2:3][CH2:4]1Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-7ac1b544c6ef4abb849682302fc7595a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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