Dichloromethane → 4-(4-chlorobenzylthio)-1-(4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl)pyrimidin-2(1H)-one
Reaction equation
[CH2:33]([Cl:34])[Cl:35].[Cl:24][c:25]1[cH:26][cH:27][c:28]([CH2:31][SH:32])[cH:29][cH:30]1.[OH:1][C:2]([CH2:3][O:4][c:5]1[c:6]([O:20][CH3:21])[cH:7][c:8](-[n:11]2[c:12](=[O:19])[n:13][c:14]([S:17][CH3:18])[cH:15][cH:16]2)[cH:9][cH:10]1)([CH3:22])[CH3:23]>>[OH:1][C:2]([CH2:3][O:4][c:5]1[c:6]([O:20][CH3:21])[cH:7][c:8](-[n:11]2[c:12](=[O:19])[n:13][c:14]([S:17][CH2:18][c:28]3[cH:27][cH:26][c:25]([Cl:24])[cH:30][cH:29]3)[cH:15][cH:16]2)[cH:9][cH:10]1)([CH3:22])[CH3:23]Participants
4
Sources & evidence
- ORD record
- ord-dee1d8d0f9ac426d8b768a93d3567e81
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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