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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1228755Generated: October 27, 2026

Hydrochloric Acid → 1-t-Butoxycarbonyl-4-{1-(4-fluorophenyl)-2-[4-(naphthalen-1-yl-butyl)piperazin-1-yl]-2-oxoethyl}-4-hydroxypiperidine

https://huagongshe.com/reaction/1228755

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantEthyl AcetateHCID 8857—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantPiperazine, 1-[4-(1-naphthalenyl)butyl]-HCID 17850645—
Reactant1-Ethyl-(3,3-dimethylaminopropyl)carbodiimideHCID 18329082—
Reactant1-t-Butoxycarbonyl-4-[carboxy-(4-fluorophenyl)methyl]-4-hydroxypiperidineHCID 22318630—
Product1-t-Butoxycarbonyl-4-{1-(4-fluorophenyl)-2-[4-(naphthalen-1-yl-butyl)piperazin-1-yl]-2-oxoethyl}-4-hydroxypiperidineHCID 17850663—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-ae1d3c4b220f43d9a967aa6832674521
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)