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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1228927Generated: November 2, 2026

Methanol → 7-Chloro-2-(difluoromethyl)-2-methylchroman-4-one

https://huagongshe.com/reaction/1228927

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantPyrrolidineHCID 31268—
Reactant1-(4-Chloro-2-hydroxyphenyl)ethanoneHCID 1051513—
Reactant1,1-Difluoropropan-2-oneHCID 3494771—
Product7-Chloro-2-(difluoromethyl)-2-methylchroman-4-oneHCID 67362099—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-cecad09bc1464d938bb01ff1e9e02f3b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)