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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1229204Generated: November 2, 2026

Hydrochloric Acid → Ethyl 1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylate

https://huagongshe.com/reaction/1229204

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantDiethyl EtherHCID 3283—
ReactantPiperazineHCID 4837—
ReactantDimethylformamideHCID 6228—
ReactantEthyl AcetateHCID 8857—
ReactantEthyl 1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-7-phenylthio-1,8-naphthyridine-3-carboxylateHCID 13849338—
ProductEthyl 1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylateHCID 13849334—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-66cffe527396473cbb0f08d7c741e171
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)