Dichloromethane → 5-Bromo-3-(1-cyclopropyl-1H-pyrazol-4-ylamino)-1-methylpyrazin-2(1H)-one
Reaction equation
[Br:10][c:11]1[c:12](=[O:19])[n:13]([CH3:18])[cH:14][c:15]([Br:17])[n:16]1.[C:20](=[O:21])([O-:22])[O-:23].[CH:1]1([n:4]2[n:5][cH:6][c:7]([NH2:9])[cH:8]2)[CH2:2][CH2:3]1.[Cl:88][CH2:89][Cl:90].[Cs+:24].[Cs+:25].[O:26]1[CH2:27][CH2:28][O:29][CH2:30][CH2:31]1.[O:34]=[C:35]([CH:36]=[CH:37][c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1)[CH:44]=[CH:45][c:46]1[cH:47][cH:48][cH:49][cH:50][cH:51]1.[O:52]=[C:53]([CH:54]=[CH:55][c:56]1[cH:57][cH:58][cH:59][cH:60][cH:61]1)[CH:62]=[CH:63][c:64]1[cH:65][cH:66][cH:67][cH:68][cH:69]1.[O:70]=[C:71]([CH:72]=[CH:73][c:74]1[cH:75][cH:76][cH:77][cH:78][cH:79]1)[CH:80]=[CH:81][c:82]1[cH:83][cH:84][cH:85][cH:86][cH:87]1.[Pd:32].[Pd:33]>>[CH:1]1([n:4]2[n:5][cH:6][c:7]([NH:9][c:11]3[c:12](=[O:19])[n:13]([CH3:18])[cH:14][c:15]([Br:17])[n:16]3)[cH:8]2)[CH2:2][CH2:3]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-07705f90cc3c47b99248386f393da571
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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