(3,5-Difluorophenyl)boronic acid → 1-{[2-(3,5-Difluorophenyl)-1,3-thiazol-4-yl]methyl}-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile
Reaction equation
[Br:1][c:2]1[s:3][cH:4][c:5]([CH2:7][n:8]2[c:9]([CH3:23])[cH:10][c:11]3[c:12]([C:19]([F:20])([F:21])[F:22])[c:13]([C:17]#[N:18])[cH:14][cH:15][c:16]23)[n:6]1.[F:24][c:25]1[cH:26][c:27]([B:32]([OH:33])[OH:34])[cH:28][c:29]([F:31])[cH:30]1>>[c:2]1(-[c:27]2[cH:26][c:25]([F:24])[cH:30][c:29]([F:31])[cH:28]2)[s:3][cH:4][c:5]([CH2:7][n:8]2[c:9]([CH3:23])[cH:10][c:11]3[c:12]([C:19]([F:20])([F:21])[F:22])[c:13]([C:17]#[N:18])[cH:14][cH:15][c:16]23)[n:6]1Participants
3
Sources & evidence
- ORD record
- ord-cfe1d02b6d854c5ead19a604d714bd55
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…