Dichloromethane → 4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1,2,4]triazin-3-ylamino)-N-methyl-N-(2-(pyrrolidin-1-yl)ethyl)benzenesulfonamide

HRID 1229723Notes

Reaction equation

HRID 1229723 reaction equation
[B:40]([Br:41])([Br:42])[Br:43].[Cl:1][c:2]1[c:3](-[c:10]2[cH:11][c:12]3[c:13]([n:14][c:15]([NH:18][c:19]4[cH:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[N:28]([CH2:29][CH2:30][N:31]5[CH2:32][CH2:33][CH2:34][CH2:35]5)[CH3:36])[cH:23][cH:24]4)[n:16][n:17]3)[c:37]([CH3:39])[cH:38]2)[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1.[Cl:44][CH2:45][Cl:46]>>[Cl:1][c:2]1[c:3](-[c:10]2[cH:11][c:12]3[c:13]([n:14][c:15]([NH:18][c:19]4[cH:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[N:28]([CH2:29][CH2:30][N:31]5[CH2:32][CH2:33][CH2:34][CH2:35]5)[CH3:36])[cH:23][cH:24]4)[n:16][n:17]3)[c:37]([CH3:39])[cH:38]2)[cH:4][c:5]([OH:8])[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 25134Boron tribromideHCID 598376744-[7-(2-chloro-5-methoxy-phenyl)-5-methyl-benzo[1,2,4]triazin-3-ylamino]-N-methyl-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide

Product 1

HCID 115268724-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1,2,4]triazin-3-ylamino)-N-methyl-N-(2-(pyrrolidin-1-yl)ethyl)benzenesulfonamide

Sources & evidence

ORD record
ord-8f5fb67ab78642aaade6798df88cd7b8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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