3-Amino-N-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)propanamide → 5-Amino-pentanoic acid {4-[3-chloro-4-(3-fluoro-benzyloxy)-phenylamino]-quinazolin-6-yl}-amide
Reaction equation
[C:34]([O:35][C:36](=[O:37])[NH:40][CH2:41][CH2:42][CH2:43][CH2:44][C:45]([NH:46][c:47]1[cH:48][c:49]2[c:50]([NH:57][c:58]3[cH:59][c:60]([Cl:73])[c:61]([O:64][CH2:65][c:66]4[cH:67][c:68]([F:72])[cH:69][cH:70][cH:71]4)[cH:62][cH:63]3)[n:51][cH:52][n:53][c:54]2[cH:55][cH:56]1)=[O:74])([CH3:38])([CH3:39])[CH3:75].[NH2:1][CH2:2][CH2:3][C:4]([NH:5][c:6]1[cH:7][c:8]2[c:9]([cH:10][cH:11]1)[n:12][cH:13][n:14][c:15]2[NH:16][c:17]1[cH:18][cH:19][c:20]([O:21][CH2:22][c:23]2[cH:24][cH:25][cH:26][c:27]([F:28])[cH:29]2)[c:30]([Cl:31])[cH:32]1)=[O:33]>>[NH2:40][CH2:41][CH2:42][CH2:43][CH2:44][C:45]([NH:46][c:47]1[cH:48][c:49]2[c:50]([NH:57][c:58]3[cH:59][c:60]([Cl:73])[c:61]([O:64][CH2:65][c:66]4[cH:67][c:68]([F:72])[cH:69][cH:70][cH:71]4)[cH:62][cH:63]3)[n:51][cH:52][n:53][c:54]2[cH:55][cH:56]1)=[O:74]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-d510790b33444ccdb16b19f6ea2d0f2e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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