Pyridine → 4-Chloro-2-[[5-[4-(trifluoromethyl)phenyl]-2,3-dihydro-2-oxo-1,3,4-oxadiazol-3-yl]methyl]phenyl 4-(chloromethyl)benzoate

HRID 1230193Notes

Reaction equation

HRID 1230193 reaction equation
[CH2:43]([Cl:44])[Cl:45].[Cl:12][c:13]1[cH:14][cH:15][c:16]([OH:36])[c:17]([CH2:19][n:20]2[c:21](=[O:35])[o:22][c:23](-[c:25]3[cH:26][cH:27][c:28]([C:31]([F:32])([F:33])[F:34])[cH:29][cH:30]3)[n:24]2)[cH:18]1.[Cl:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([C:7](=[O:8])[Cl:9])[cH:10][cH:11]1.[cH:37]1[cH:38][cH:39][n:40][cH:41][cH:42]1>>[Cl:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([C:7](=[O:8])[O:36][c:16]2[cH:15][cH:14][c:13]([Cl:12])[cH:18][c:17]2[CH2:19][n:20]2[c:21](=[O:35])[o:22][c:23](-[c:25]3[cH:26][cH:27][c:28]([C:31]([F:32])([F:33])[F:34])[cH:29][cH:30]3)[n:24]2)[cH:10][cH:11]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 701364-(Chloromethyl)benzoyl chlorideHCID 10474339Bms-191011

Product 1

HCID 218521004-Chloro-2-[[5-[4-(trifluoromethyl)phenyl]-2,3-dihydro-2-oxo-1,3,4-oxadiazol-3-yl]methyl]phenyl 4-(chloromethyl)benzoate

Sources & evidence

ORD record
ord-f9a862dadb9a4f28a84b1f278d7bddd1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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