Chloroform → 1-Benzyl-2-(chloromethyl)pyrrolidine

HRID 1230233Notes

Reaction equation

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH:9]([CH2:13][OH:14])[CH2:10][CH2:11][CH2:12]1.[CH:19]([Cl:20])([Cl:21])[Cl:22].[S:15]([Cl:16])([Cl:17])=[O:18]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH:9]([CH2:13][Cl:17])[CH2:10][CH2:11][CH2:12]1

Participants

Reactant 3

HCID 6212Chloroform

HCID 24386Thionyl Chloride

HCID 562951(1-Benzylpyrrolidin-2-yl)methanol

Product 1

HCID 30426421-Benzyl-2-(chloromethyl)pyrrolidine

Sources & evidence

ORD record: ord-0d44ffd90a344812b3b8cc015c250862
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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