4-Cyanophenylboronic acid → 4-[5-(1-Isopropyl-piperidin-4-yloxy)-2-(morpholine-4-carbonyl)-indol-1-yl]-benzonitrile

HRID 1230576Notes

Reaction equation

HRID 1230576 reaction equation
[C:28](#[N:29])[c:30]1[cH:31][cH:32][c:33]([B:36]([OH:37])[OH:38])[cH:34][cH:35]1.[CH:1]([CH3:2])([CH3:3])[N:4]1[CH2:5][CH2:6][CH:7]([O:10][c:11]2[cH:12][c:13]3[cH:14][c:15]([C:20](=[O:21])[N:22]4[CH2:23][CH2:24][O:25][CH2:26][CH2:27]4)[nH:16][c:17]3[cH:18][cH:19]2)[CH2:8][CH2:9]1>>[CH:1]([CH3:2])([CH3:3])[N:4]1[CH2:5][CH2:6][CH:7]([O:10][c:11]2[cH:12][c:13]3[cH:14][c:15]([C:20](=[O:21])[N:22]4[CH2:23][CH2:24][O:25][CH2:26][CH2:27]4)[n:16](-[c:33]4[cH:32][cH:31][c:30]([C:28]#[N:29])[cH:35][cH:34]4)[c:17]3[cH:18][cH:19]2)[CH2:8][CH2:9]1

Participants

3

Reactant 2

HCID 27343264-Cyanophenylboronic acidHCID 11717680(5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)(morpholino)methanone

Product 1

HCID 167395914-[5-(1-Isopropyl-piperidin-4-yloxy)-2-(morpholine-4-carbonyl)-indol-1-yl]-benzonitrile

Sources & evidence

ORD record
ord-b39983a1ba0342c399cd234aaecbcfed
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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