Methanol → 3-(2-fluoro-1-fluoromethyl-ethyl)-8-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamine
Reaction equation
[CH3:22][OH:23].[F:1][CH2:2][CH:3]([CH2:4][F:5])[N:6]1[CH2:7][CH2:8][c:9]2[c:10]([cH:13][c:14]([O:20][CH3:21])[c:15]([N+:17]([O-:18])=[O:19])[cH:16]2)[CH2:11][CH2:12]1>>[F:1][CH2:2][CH:3]([CH2:4][F:5])[N:6]1[CH2:7][CH2:8][c:9]2[c:10]([cH:13][c:14]([O:20][CH3:21])[c:15]([NH2:17])[cH:16]2)[CH2:11][CH2:12]1Participants
3
Sources & evidence
- ORD record
- ord-e5ff29002ae447408794a0a1ec9e4646
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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