Ethanol → tert-Butyl 4-(2-aminoethyl)piperazine-1-carboxylate

HRID 123068Notes

Reaction equation

HRID 123068 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][N:16]2[C:17](=[O:18])[c:19]3[c:20]([cH:21][cH:22][cH:23][cH:24]3)[C:25]2=[O:26])[CH2:12][CH2:13]1.[CH3:30][CH2:31][OH:32].[NH2:28][NH2:29].[OH2:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][NH2:16])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 702EthanolHCID 962WaterHCID 9321HydrazineHCID 22397705tert-Butyl 4-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]piperazine-1-carboxylate

Product 1

HCID 1514400tert-Butyl 4-(2-aminoethyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-008c5ba2670748a8a18a799fec152545
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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