HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1230685Generated: October 31, 2026
N-methyl-2-pyrrolidone → 2-(2-(4-((6-Chloro-3-pyridinyl)sulfonyl)-2-(1-propyn-1-yl)-1-piperazinyl)-5-pyrimidinyl)-1,1,1-trifluoro-2-propanol
https://huagongshe.com/reaction/1230685
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 1-((6-Chloro-3-pyridinyl)sulfonyl)-3-(1-propyn-1-yl)piperazine | HCID 77230767 | — |
| Reactant | 2-(2-Chloropyrimidin-5-yl)-1,1,1-trifluoropropan-2-ol | HCID 86670360 | — |
| Product | 2-(2-(4-((6-Chloro-3-pyridinyl)sulfonyl)-2-(1-propyn-1-yl)-1-piperazinyl)-5-pyrimidinyl)-1,1,1-trifluoro-2-propanol | HCID 86670426 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (5/10) |
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| ORD ID | ord-e6081115f7984bcb93b1a9aaf1d490a8 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (5/10) |
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