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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1230795Generated: October 31, 2026

Toluene → 1-(2-Diethylaminoethyl)-4-bromo-6-[3-(2-oxo-1,3-oxazolin-3-yl)-1-propynyl]-3-hydroxy-3-(2-chlorophenyl)oxindole

https://huagongshe.com/reaction/1230795

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant3-(2-Oxo-1,3-oxazolin-3-yl)-1-propyneHCID 11987859—
Reactant1-(2-Diethylaminoethyl)-3-hydroxy-3-(2-chlorophenyl)-4-bromo-6-iodooxindoleHCID 18518654—
Product1-(2-Diethylaminoethyl)-4-bromo-6-[3-(2-oxo-1,3-oxazolin-3-yl)-1-propynyl]-3-hydroxy-3-(2-chlorophenyl)oxindoleHCID 18518662—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-83aba75cdcb1474ba93f184490f2f30c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)