Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1231044Generated: November 1, 2026

Tetrahydrofuran → Tert-butyl 5-[3-(3-chloro-5-fluorophenyl)-1-hydroxy-2-nitropropyl]-2-(2,2-dimethylpropoxy)morpholine-4-carboxylate

https://huagongshe.com/reaction/1231044

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
ReactantTetrabutylammoniumHCID 16028—
ReactantFluoride IonHCID 28179—
Reactant1-Chloro-3-fluoro-5-(2-nitroethyl)benzeneHCID 68558923—
ReactantTert-butyl 2-(2,2-dimethylpropoxy)-5-formylmorpholine-4-carboxylateHCID 91358954—
ProductTert-butyl 5-[3-(3-chloro-5-fluorophenyl)-1-hydroxy-2-nitropropyl]-2-(2,2-dimethylpropoxy)morpholine-4-carboxylateHCID 77514635—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-5c78b79bf39c4986ad6f1c3c632caa62
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)